Tylenol Ultra: With Caffeine?! By Adam Hollett on Sep 27, 2007 - Updated Oct 15, 2011

As a sufferer of frequent migraines, I am constantly looking for a better pain reliever. Visiting the drug store one night, I found this new product on sale, so I thought I'd give it a try. Several days later, when the pain hit, I discovered how quickly they worked.

The label describes the product as 'Acetaminophen with PAIN RELIEF ENHANCER' - but what does that mean? Checking the back of the label explains that this 'enhancer' is really just caffeine. 65mg of it per pill, roughly the amount in your typical cup of coffee. Further text on the label explains that a combination of acetaminophen and caffeine help relieve pain quicker in a pair rather than on their own. It seems to be true. When I first took a pair of these tablets, my headache was gone quickly, and stayed gone. I cannot deny that the pills work. However, their contents, while they are most likely safe if they are an over-the-counter drug, are somewhat unnerving. As an avid caffeine imbiber I don't mind, but I would not recommend these pills to anyone who is sensitive to the stimulant.

These pills have a flashy, easy-to-open package (they are also available in child-resistant packaging), and are intended for people with frequent pain that want quick relief. For anyone else, I would recommend sticking with extra-strength Tylenol, just to be safe.