Thanks to Desitin, my son has never had a serious diaper rash. I was using the regular Desitin at first before I got the Maximum Strength. One day his little booty got a little red so I went and got the Maximum Strength Desitin and put it up there and it totally went away. Ever since then I've being using the Maximum Strength Desitin to prevent diaper rashes and he hasn't even had a little redness since. Any type of Desitin is good, but I highly recommend using the Maximum Strength because it has 40% zinc oxide vs. the Desitin Rapid Relief Cream which only has 13% zinc oxide. The Maximum Strength offers a larger amount of proection than the Rapid Relief, so it'll be a whole lot better to start with. It doesn't only protect against diaper rashes, but it also helps soothe and heal them. I decided to even use Desitin when I learned that doctors don't recommend using Baby Powder unless you're very careful with it. I'm glad I decided to use Desitin and I really hope alot of parents are using it. It works good. It seals out wetness. It is a anti-inflammatory and keeps the skin from being irritated.