I use regular aspirin for when i have a very mild pain that I just need a little bit of relief for. Aspirin is good for aches and pains, toothaches, pain associated with fever, colds, and flus, and arthritis pain. I tried Exchange select Aspirin, it is a generic brand that works just as effectively as the brand names, and it is alot less expensive than most other bottles. I love the fact that it is caffeine free, so I don;t have to worry about taking too much, and sodium free, so theres no worry about too much salt. at 325 mg per tablet, I only need to take two or three to get the pain to go away. I like that the bottle is childproof, yet easy for an adult to open. Exchange Select's aspirin also has a micro-thin coating, making them easy to swallow. I like their product, and will use them in the future.