I own a 1999 Lexus RX 300. This is a car that was first leases when it became hot on the market, and later purchased completely. After having driven this car for over eight years, I can say that this is one of the most reliable vehicle I've been in.
The car does eat up gas since it's an SUV, but if you don't mind that, it's definietly a great car. I haven't had any major issues with the car so far - I haven't even had to change a single light yet! The woodpanel on the dashboard, as well as the leather on the seats, have remained in good condition even after so many years with a frequent driver. It does have over 140, 000 miles but it still runs fine without any weird noises or feel.
During the last couple of years, Lexus has become one of the nicer luxury cars out there, and I plan on upgrading to the newer RX models in the future.