When it comes to pain relief, I always trust Motrin Ibuprofen to relieve my pain where it hurts. I usually start off by taking 400 mg of Motrin and it usually takes around 45 minutes for it to reach its full effect. The only downfall to this medicine is its short acting. Usually it only wards off pain on me for about two hours. It is safe to use and I have never experienced any side effects. Its convenient to use and the bottle can fit right in a woman's purse, so transporting this medicine isn't a problem. The airtight bottle assures moisture stays out and away from the product The lid is child proof so I don't have to worry about my Little ones getting in and taking this product. Overall I rate this product well except for the fact it is short acting.