Once my daughter moved on from the fluoride-free infant toothpaste, I had a hard time finding one that didn't cause a reaction on her mouth. Her pediatrician finally suggested I try a "natural" children's toothpaste and that is when I found Tom's of Maine. I have been very pleased with it. My daughter loves the "silly strawberry" flavor and the colorful packaging. She doesn't miss her favorite characters, like on the other children's toothpastes out there. The only real downside I see is that the cap is sometimes a bit hard for her to get open on her own. And for an independent child, it can be discouraging for her to have to ask for help. But once the cap is open, she can easily and happily brush her own teeth with this great natural toothpaste.